Now in Beta

Clinical AI for
oncologists
worldwide.

Luminomics synthesizes evidence from 300,000+ cancer research papers to deliver real-time, literature-backed clinical decision support at the point of care.

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300K+
Cancer research papers indexed
5+
Cancer types covered
92
Evidence clusters discovered
3s
Average query response time

Built for the way oncologists actually work

Every feature designed around real clinical workflows — not lab benchmarks.

🔍

Evidence-First Search

Semantic search across 300,000+ papers with BGE Cross-Encoder reranking. Ranked by clinical relevance, not keyword match.

🧬

Mutation-Aware Matching

KRAS · BRAF · MSI-H · HER2 · NTRK — biomarker-specific evidence retrieval with 6-dimensional case matching.

📋

NCCN/ASCO Integration

Real-time guideline cross-referencing. Every recommendation is grounded in Category 1 evidence from leading guidelines.

💊

Drug Safety Checks

Automatic interaction screening across oncology regimens. Age-adjusted dose recommendations with renal function considerations.

🧪

Clinical Trial Matching

Live clinicaltrials.gov integration. Matches patients to open trials by mutation, stage, line of therapy, and geography.

🎯

5-Tier Evidence Grading

Automated trust scoring across 45,000+ papers. Retracted literature flagged. Grade A–C evidence clearly distinguished.

From question to decision in seconds

1

Ask in plain language

Describe your patient — mutation, stage, line of therapy, comorbidities.

2

AI searches the evidence

Semantic search + HyDE expansion retrieves the most relevant papers globally.

3

Evidence is ranked & verified

Cross-Encoder reranking and 5-tier trust scoring filter noise and flag retracted studies.

4

Structured recommendation

Receive a NCCN-grounded recommendation with citations, cautions, and open trials.

// Live query example
Pembrolizumab vs. bevacizumab in MSI-H/dMMR metastatic CRC (KEYNOTE-177)
NEJM 2020 Grade A Sim: 0.903
Nivolumab + ipilimumab in MSI-H/dMMR mCRC (CheckMate-142)
J Clin Oncol 2020 Grade A Sim: 0.888
Efficacy of pembrolizumab in MSS, TMB-high metastatic CRC
Cancer 2021 Grade B Sim: 0.767
RECOMMENDATION
Primary: Pembrolizumab 200mg Q3W — first-line for MSI-H/dMMR mCRC [STRONG · HIGH]

Every answer backed by traceable evidence

Luminomics doesn't generate opinions — it retrieves, ranks, and synthesizes published evidence, then presents it in a structured clinical format with full citation trails.

Retracted papers are automatically excluded. Evidence grades are transparent. You always know exactly why a recommendation was made.

  • Automatic retraction detection across all indexed papers
  • Recommendation strength aligned with GRADE methodology
  • Full PMID citations for every clinical statement
  • Drug interaction screening with dose-adjustment alerts

Designed for every oncology context

01 · TREATMENT SELECTION

First & second-line therapy

Compare FOLFOX, FOLFIRI, immunotherapy, and targeted regimens for any mutation profile with current evidence and trial data.

02 · ELDERLY PATIENTS

Geriatric dose optimization

Age-adjusted recommendations with renal function considerations, frailty scoring, and comorbidity-aware drug interaction alerts.

03 · BIOMARKER QUERIES

Precision oncology support

Instant evidence synthesis for KRAS G12C, BRAF V600E, MSI-H/dMMR, HER2, NTRK fusions, and emerging biomarkers.

04 · TRIAL MATCHING

Clinical trial eligibility

Real-time matching to recruiting trials worldwide by mutation, stage, prior therapy, and geographic location.

05 · GUIDELINE LOOKUP

NCCN/ASCO at a glance

Instant access to Category 1 recommendations from NCCN and ASCO guidelines, cross-referenced with primary literature.

06 · SAFETY REVIEW

Pre-prescription drug check

Automated screening for high-risk interactions — warfarin + fluorouracil, bevacizumab + anticoagulants, and more.

Ready to bring evidence
to every decision?

Luminomics is currently in private beta. We are onboarding oncologists and cancer centers for early access.

Request Early Access →